AGBL offers Vitrolife products for Preimplantation Genetic Testing. Vitrolife directly supports the PGT-A and PGT-M products, along with the associated software. It provides solutions for Preimplantation Genetic Testing for Aneuploidy (PGT-A) by using the VeriSeq PGS kit and Karyomapping using the Human Karyomap 12 Beadchip provides a rapid solution for providing insight into inheritance of single gene disorders.
PGT-A (Preimplantation Genetic Testing for Aneuploidy determines the chromosomal status of an embryo by screening all 23 chromosome pairs prior to transfer in an IVF cycle. PGT-A can be performed using next-generation sequencing (NGS) using the VeriSeq PGS Solution. The VeriSeq PGS solution can screen all 24 chromosomes in as little as 12 hours for an accurate, efficient view of the number of chromosomes in an embryo. It was extensively validated in a large pre-clinical, multisite study and reliably detects chromosome aneuploidies in low DNA input samples across multiple sites, whether from biopsy of a single cell or a few cells.Preimplantation genetic testing for Monogenic Disease (PGT-M) assesses embryos to help prevent the transmission of an inherited genetic disorder to children. The HumanKaryomap-12 DNA Analysis Kit is a comprehensive genome-wide test available at the single-cell level. It provides insight into the inheritance of single-gene defects. This BeadChip array targets ~300,000 of the most informative markers in the genome for efficient genome-wide coverage. Karyomapping uses biomarkers within the genome to assess the likelihood of an embryo carrying a gene variant involved in a single-gene disorder.